It is well known that the bacteria can colonize moist skin surfaces and can cause a greenish discolouration of skin, nails, clothes, and surgical dressings (48, 62, 64, 65). Mayo Clinic is a not-for-profit organization. Clin Interv Aging 2015; 10: 265267. If your bronchitis is caused by bacteria, you usually stop being contagious 24 hours after starting antibiotics. MNT is the registered trade mark of Healthline Media. 2004-2023 Healthline Media UK Ltd, Brighton, UK, a Red Ventures Company. Corynebacterium nigricans sp. (b) Diffuse blue discolouration with an ashen hue on dorsal side of the foot. Conditions that might cause it include: Mayo Clinic does not endorse companies or products. Sweating is an important bodily function that keeps you cool during hot weather and tough workouts. This form of colored sweat is seen when normal perspiration at the skin surface interacts with other compounds, such as dyes (from a new pair of jeans, perhaps), chemicals (a la sunless tanning sprays) or chromogenic bacteria on the skin (bacteria that produce pigments), Dr. Friedmann says. This tentative diagnosis has been strengthened by complete remission after antibacterial treatment, combining systemic and topical erythromycin in all cases. Symptoms of the stomach flu typically last 1 to 3 days. Such psychological effects are likely very familiar to our hyperhidrosis readers and we welcome chromhidrosis sufferers to our community. Chang YC, Anderson N, Soeprono F. Bilateral facial pigmentation. Due to its production of red colour, the presence of S. marcescens has often been mistaken for sweating of blood (hematohidrosis) (45). PloS One 2015; 10: e0125428. JAMA Dermatol 2013; 149: 13391340. [2] It is caused by the deposition of lipofuscin in the sweat glands. Panagoulias GS, Basagiannis CS, Tentolouris N, Stavropoulou E, Karnesis L. Colored sweat caused by pseudochromhidrosis. The blue toilet seat phenomenon is still somewhat of a mystery, but signs point to a condition called chromhidrosis. It's also important to talk to your doctor about any emotional distress you're experiencing in relation to your chromhidrosis, as feeling self-conscious about it is totally normal, Dr. King says: "Although it's a rare condition, you're not alone there are therapists and counseling available to help you out. She had started daily 25 mg promethazine due to pruritus 6 months earlier. Effect of prothazin (promethazine hydrochloride) on sweat gland activity. Make a donation. (blue colour), Corynebacterium spp. |, Creative Commons Attribution-NonCommercial 4.0 International License. According to the medical journal Pediatrics, chromhidrosis can be treated with topical capsaicin cream 0.025% (applied to the affected skin 1-2 times per day). There is no cure for rosacea. Pseudochromhidrosis. Dermatology 1999; 199: 149152. If sweat changes color, contact a doctor, who may rule out other causes before diagnosing chromhidrosis. In pseudochromhidrosis, a far more common disorder, sweat becomes colored after secretion from the sweat gland. Chromhidrosis is a harmless condition. Depending on the cause of your child's pink eye, signs and symptoms usually improve within a few days to two weeks. Whether promethazine is the sole trigger is currently unknown. Semkova K, Gergovska M, Kazandjieva J, Tsankov N. Hyperhidrosis, bromhidrosis, and chromhidrosis: Fold (intertriginous) dermatoses. Experts: GARD is not currently aware of a specialist directory for this condition. Microbiol Immunol 2017; 61: 490496. Bacillus cereus: 2 isolates; one with a blue tint and one without. Red facial pseudochromhidrosis. Gaffney DC, Cooper HL. In severe cases, your health care provider may suggest surgery to remove the sweat glands or to disconnect the nerves related to producing too much sweat. Liu GY, Nizet V. Color me bad: microbial pigments as virulence factors. Park JG, Prose NS, Garza R. Eccrine Chromhidrosis in an adolescent with sickle cell disease. You may opt-out of email communications at any time by clicking on J Biochem 1977; 81: 843850. This type of hyperhidrosis may cause sweating all over the body. However, no matter the type or types that are causing your symptoms, working with a skin specialist can help get your symptoms under control and improve your skin. Clin Microbiol 2012; 50: 31523158. Coloured sweat in two brothers: first report of familial chromhidrosis. is commonly associated with chromhidrosis. Eccrine chromhidrosis may occur anywhere on the body, as eccrine glands are widely distributed, except in areas such as the lips. (9094). 2018; doi:10.1016/j.jaad.2018.07.002. Accessed June 28, 2022. Afra S, Makhdoumi A, Matin MM, Feizy J. Prodigiosin pigment of Serratia marcescens is associated with increased biomass production. Smith CC, et al. Four bacteria are known to be involved in infectious pseudochromhidrosis: Bacillus spp. Sweating, excessive. Dermatol Online J 2014; 21. pii: 13030/qt73k8k695. Chang T, Rosch JW, Gu Z, Hakim H, Hewitt C, Gaur A, et al. Heavy sweating can disrupt your day and cause social anxiety and embarrassment. G20 with specific anticancer activity. An ashen hue was observed primarily on hands, feet, and neck (female patient), and right pectoral region (male patient). The best treatment depends on the type of chromhidrosis: Treatment for this type of chromhidrosis either aims to reduce the amount of sweat or to induce the sweat and empty the glands. Br J Dermatol 2000; 142: 12191220. Here's What Your Body's Trying to Tell You. This process might involve your doctor testing skin scrapings, secretion smears and extraction samples from clothing. Appl Biochem Biotechnol 2011; 164: 767779. Sweat may be yellow, green, blue, brown, or black. Because apocrine glands don't start functioning until puberty (when hormonal stimulation begins), this form of chromhidrosis is typically more prominent when a person is younger, with symptoms becoming less severe as they age (as apocrine secretion tapers off). Takita Y, Ichimiya M, Yamaguchi M, Hamamoto Y, Muto M. A case of pseudochromhidrosis due to dihydroxyacetone. Arch Microbiol 2018; 200: 989999. It may be associated with hyperhidrosis. Pigment production by Haemophilus parapertussis. triggered by topiramate (an antiepileptic drug) (38). The underlying skin was normal. Promethazine was stopped 1 month after presentation with no change in colour intensity. Dr. Hines conducts a comprehensive evaluation and rules out more serious causes. Upper respiratory infection symptoms include coughing, runny nose, sneezing and throat pain. Med Mal Infect 2015; 45: 436440. Polat M, Dikilitas M, Gozubuyukogullari A, Alli N. Apocrine chromhidrosis. A novel red pigment from marine Arthrobacter sp. reported a novel Corynebacterium spp. Eccrine glands secrete a clear, odorless fluid that. July 13, 2022. Tracking your daily activities for two to three weeks such as what you've eaten and any chemicals you've come into contact with leading up to your doctor's appointment can be helpful in determining your triggers and what the potential culprits might be. Regular sweat is clear or slightly cloudy in color, but people with chromhidrosis notice a colored sweat. Treatment for eccrine chromhidrosis tends to involve reducing or eliminating contact with the dye, chemical, or heavy metal responsible for the discoloration. A more common type of discolored sweat is called pseudochromhidrosis. Red eccrine chromhidrosis with review of literature. While it can occur at any age, its most often noticeable after puberty. Symptoms are usually worse during the first 2 to 3 days, and this is when you're most likely to spread the virus. Additional investigations were performed, including blood and urine analyses. Despite determining survival, pathogenicity, and virulence among microorganisms, we hypothesize that most pigments are mainly produced only under favourable conditions (of pH, temperature, hydration levels, metabolism rate, oxygen tension, growth substrates, etc.). Bernard K. The genus corynebacterium and other medically relevant coryneform-like bacteria. Indian J Dermatol Venereol Leprol 2012; 78: 756758. Chromhidrosis is a harmless skin condition, but because colored sweat can be a symptom of something more serious, it's important to check in with your doctor or dermatologist for an official diagnosis. The pigments causing the colour palette seen in this disorder appear to be of major importance for microorganisms. Fig. Epilepsia 2003; 44: 974976. "Because of its wide range of underlying causes, eccrine chromhidrosis can happen at any age," Dr. Friedmann says. Chromhidrosis is harmless, but it can cause embarrassment or distress that may lead to depression or anxiety. Iranian J Basic Med Sci 2017; 20: 13311338. Lipofuscins are yellow-brown pigment granules made of fat-like residues. Mayo Clinic on Incontinence - Mayo Clinic Press, NEW The Essential Diabetes Book - Mayo Clinic Press, NEW Ending the Opioid Crisis - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, Book: Mayo Clinic Family Health Book, 5th Edition, Health Products for Men and Women from Mayo Clinic Store, Newsletter: Mayo Clinic Health Letter Digital Edition. Singal A, Thami GP. Due to her reports of hypohidrosis, a sweat provocation test with following sweat pH measurements (Jenway pH meter, Model 3510, Cole-Parmer, Staffordshire, UK) were performed. 4. This is a rare dermatological disorder named infectious pseudochromhidrosis. Role of melanin pigment in expression of Vibrio cholerae virulence factors. The isolates were initially identified by morphology, Gram stain, haemolysis on blood agar, penicillin susceptibility, and motility. Cases of red, blue, green, yellow, pink, and black sweat have been reported. J Bacteriol 1953; 65: 509510. You can use pain relievers to feel better. As you produce sweat, the body cools down. However, patients with the condition report stress and embarrassment, as well as anxiety and depression related to their symptoms. Cardiovascular health: Insomnia linked to greater risk of heart attack. Chromhidrosis is a rare chronic condition that causes sweat to turn black, blue, green, yellow, or brown. The authors also suggested that topiramate reduces aquaporin-5 expression in the skin. For patients with pseudochromhidrosis, antimicrobial medications may help balance bacteria to reduce colored sweat. Pediatr Dermatol 2018; 35: 448452. Eccrine chromhidrosis can affect the skin over any body area but is often worst on the palms and soles where eccrine sweat glands are most concentrated. It can be alarming when these uneven, wart-like, waxy bumps suddenly show up on your skin, but they're not an infection, and they're not contagious. While it isnt life-threatening, chromhidrosis often causes emotional distress. All tests were normal, apart from a slightly increased alkaline phosphatase (ALP) of 122 U/l (reference range 35105 U/l). Accepted Oct 14, 2019; E-published Oct 14, 2019, Corr: Christoffer Ingvaldsen, Department of Plastic and Reconstructive Surgery, Rikshospitalet, Oslo University Hospital, Postboks 4950 Nydalen, NO-0424 Oslo, Norway. reported that the production of prodigiosin is highly dependent on temperature, pH, and other environmental factors (86). Clin Exp Dermatol 2004; 29: 548549. The primary treatments for apocrine chromhidrosis are topical agents antiperspirant (such as Drysol), to temporarily plug the pores causing you trouble, and capsaicin cream, to deplete nerve cells of Substance P, "an important chemical that controls aprocrine gland secretion," Dr. Friedmann says. J Dermatol 2006; 33: 230231. "Your doctor can run the necessary tests to rule out more serious causes of colored sweat, such as infection, jaundice, hematidrosis (bloody sweat) and poisoning," Hadley King, MD, New York City-based board-certified dermatologist, tells LIVESTRONG.com. and Corynebacterium spp. We encourage you to subscribe to our email alerts and blog to stay on top of sweat-related news, research, and events. de Carolis P, Magnifico F, Pierangeli G, Rinaldi R, Galeotti M, Cevoli S, et al. Infant with chromhidrosis. Here's why: The culprit behind apocrine chromhidrosis is lipofuscin. Noroviruses are highly contagious. Its wise to see a doctor about colored sweat. Several techniques can, Medical News Today has strict sourcing guidelines and draws only from peer-reviewed studies, academic research institutions, and medical journals and associations. Its impossible to prevent melasma. Oxidation of lipofuscin, as well as the increase in number of lipofuscin granules, are thought to cause the skin discolouration (4, 5). J Am Acad Dermatol 2005; 53: 869871. Please tell us where you sweat so we can help you and others. Odanaka K, Iwatsuki M, Satho T, Watanabe M. Identification and characterization of a brilliant yellow pigment produced by Bordetella pertussis. ALP had also been above upper reference limit prior to the presentation of blue discolouration (with no known or suspected cause). Drewnowska JM, Zambrzycka M, Kalska-Szostko B, Fiedoruk K, Swiecicka I. Melanin-like pigment synthesis by soil bacillus weihenstephanensis isolates from northeastern Poland. Shulka et al. This may be startling or alarming to anyone who isnt aware of the condition. American Academy of Dermatology Association. Although the condition is long-term, some patients may experience a decrease in discolored sweat as they age. Leonard et al. In: Dermatology: An Illustrated Colour Text. Others may have such mild sweat discoloration that they do not even notice it. The condition is harmless, though, so pregnant people shouldn't worry about blue or purple toilet seats, although it's something you can certainly mention to your ob-gyn. Apocrine chromhidrosis over dorsum of foot: a case report. True chromhidrosis is a rare condition characterized by the secretion of colored sweat from apocrine or eccrine sweat glands. Full texts and reference lists were reviewed. reported blue skin discolouration due to Bacillus spp. Primary focal hyperhidrosis. Keeping the area clean and wearing different clothes can help resolve and. Electrophysiological study in 2 children with transient hypohidrosis induced by topiramate. Marks JG, Jr. Chromhidrosis is quite rare with limited information about the percentage of people potentially affected. Curr Genet 2015; 61: 309324. [A woman with blue sweat]. Int J Dermatol 2010; 49: 562564. Both adults were treated with oral erythromycin, 250 mg 3 times a day, and topical clindamycin 2 times a day for 10 days. However, when it does develop, there are ways to improve its appearance, and there are some treatments that are safe during pregnancy. Sign up for free, and stay up to date on research advancements, health tips and current health topics, like COVID-19, plus expertise on managing health. This site complies with the HONcode standard for trustworthy health information: verify here. Sweat may be yellow, green, blue, brown, or black. Chromhidrosis is a rare chronic condition that causes sweat to turn black, blue, green, yellow, or brown. J Bacteriol 2010; 192: 30683077. People sweat due to heat, stress, and a range of other causes. Sports + Sweating Playbook V2: Running Cold Winter Workout Tips to Avoid Frostbite & Hypothermia SPORTS + SWEATING PLAYBOOK VOLUME 1: GEAR. https://www.aad.org/public/diseases/a-z/hyperhidrosis-overview. If youre dealing with discolored sweat, schedule a visit with a dermatologist to get answers, rule out more serious conditions, and learn about treatment options. Rodriguez-Martin M, Rodriguez MS, Cabrera AN. This hypothesis is strengthened by the observations found in some of the IPCH case reports. reviewed pigment production in Corynebacterium spp., and reported that carotenoid production is one of many important virulence factors (59). Pseudomonas aeruginosa blue-green IPCH (36, 48, 62): P. aeruginosa is a Gram-negative, aerobic coccobacillus, which is widespread in nature (63). Some of them are. Other than. While it doesnt threaten your health, seborrheic keratosis can have a major impact on your confidence and self-esteem. In this article, learn more about what chromhidrosis is, what causes it, and what treatments are available. Bromhidrosis can affect all age groups, races, and both sexes. information highlighted below and resubmit the form. Dermoscopy of the discoloured areas revealed diffuse superficial pigmentation and an unmodified skin pattern (as postulated by Pistone et al. Prevention This goes beyond the sweating from being in a hot environment, exercising, or feeling anxious or stressed. Williamson et al. Greenberg L. Serratia marcescens in human affairs. Chromhidrosis causes the sweat glands to secrete colored sweat. Turnbull PCB. Her scalp, hair, anterior and dorsal trunk, palms, and feet were surprisingly dry. Microorganisms may produce pigments to increase the likelihood of survival. Other causes of bronchitis aren't contagious. Correlation between pigment production and amino acid requirements in Bacillus subtilis. Skin Pharmacol Physiol 2006; 19: 296302. Some people with chromhidrosis may report a feeling of warmth or a prickly sensation before the onset of colored sweat. Review of reported cases of chromhidrosis. Chromhidrosis is a rare condition with a characteristic presentation of the secretion of colored sweat and was first reported by Yonge in 1709. Sweating also occurs, especially on your palms, when you're nervous. Front Microbiol 2015; 6: 1463. Williamson NR, Simonsen HT, Ahmed RA, Goldet G, Slater H, Woodley L, et al. AMA Arch Derm Syphilol 1954; 69: 449471. International Hyperhidrosis Society. With pseudochromhidrosis, sweat takes on an unusual color after secretion from the sweat gland as it comes in contact with dyes, chemicals, or chromogenic bacteria on the skin (bacteria that produce pigments.). Canale-Parola E. A Red pigment produced by aerobic sporeforming bacteria. 7th ed. Hyperhidrosis (hi-pur-hi-DROE-sis) is excessive sweating that's not always related to heat or exercise. Alcohol wipes from (a) hands and (b) neck easily removed the discolouration and revealed its blue colour. Moreover, there is no clear consensus in terms of disease triggers, causative microorganisms, and factors contributing to the clinical presentation of coloured sweat. The virus can remain in your stool for up to two weeks or more after recovery. Certain situations stimulate the apocrine glands and make this discoloration more likely to occur: In people with eccrine chromhidrosis, the discoloration usually happens because the person has ingested: Pseudochromhidrosis is more common, and it occurs when the skin comes into contact with: The IHS also point to other health issues that can cause sweat to change color: It is a good idea to see a doctor about colored sweat. The oxidation may be triggered by chronic exposure to copper (e.g. Hand-foot-and-mouth disease is most commonly caused by a coxsackievirus. One of the B. cereus strains found produced blue pigments on blood agar, but the other did not (Fig. Using this easy-to-remember criteria increases the chances of detecting changes in moles that may suggest melanoma, the deadliest type of skin cancer. In apocrine chromhidrosis, apocrine glands release colored sweat affecting mostly the face, ears, scalp, and trunk. A case of generalized red sweating. Combined use of ranitidine (H2-recepter antagonist) and lansoprazole (proton pump inhibitor) may trigger Bacillus colonization, as reported by Hill et al. A single copy of these materials may be reprinted for noncommercial personal use only. Transient hypohidrosis induced by topiramate. The blue discolouration appeared 23 weeks after his wifes. See below for methods for culture and identification of bacteria, and results. Keum DI, Hong H, Lee SH, Ahn SK. Bromhidrosis is foul-smelling body odor related to your sweat. https://www.uptodate.com/content/search. Bilateral facial apocrine chromhidrosis. Bull Soc Fr Dermatol Syphiligr 1965; 72: 444447. Pigments do this by interfering with the host immune system and/or provoking inflammatory damage to cells and tissues (83). Serratia marcescens red/pink IPCH (4547): S. marcescens is a Gram-negative, facultatively anaerobic, and saprophytic bacteria belonging to the Enterobacteriaceae family (60, 61). Chromhidrosis has several subtypes, which are described separately on DermNet. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. And the sweating usually happens on both sides of the body. Apocrine chromhidrosis involving the areolae in a 15-year-old amateur figure skater. Dr. Hines has extensive experience in both common and rare conditions. They recorded a slightly decreased pH on the surface of the skin of their patient and proposed that this could be a result of the treatment provided. The color and the vividness of the shade can vary from person to person. J Pak Med Assoc 2013; 63: 11921194. Facial and axillary apocrine chromhidrosis. Labouche F. Pseudochromhidrose infectieuse: une tude de cas et une revue de la littrature. If you are a Mayo Clinic patient, this could There are also several case reports where IPCH has been suspected despite negative cultures (5, 43, 44, 51, 66). Chromhidrosis is a rare, chronic condition characterized by color in your sweat. To diagnose this issue, a doctor performs a physical examination and asks about when and where the colored sweat appears. Castela et al. To provide you with the most relevant and helpful information, and understand which Heider SA, Peters-Wendisch P, Wendisch VF. Asahina M, Poudel A, Hirano S. Sweating on the palm and sole: physiological and clinical relevance. There is a problem with "Finding and stopping the specific cause is paramount.". A type of chromhidrosis known as pseudochromhidrosis may be a slightly more plausible culprit. Cawley EP, Hsu YT, Sturgill BC, Harman LE, Jr. Lipofuscin (wear and tear pigment) in human sweat glands. Saff DM, Owens R, Kahn TA. The goal of treatment for chromhidrosis is to reduce symptoms in order to also reduce any related psychosocial impacts or stigma. Learning the ABCs of melanoma could save your life. Epilepsia 2001; 42: 13631365. They can rule out more serious causes and recommend any necessary treatment. Highly regarded dermatologist and dermatopathologist Yvonne Hines, MD, and the team at Hines Dermatology Associates diagnose and treat a full range of conditions affecting the skin, including rare conditions such as chromhidrosis. Insight of genus corynebacterium: ascertaining the role of pathogenic and non-pathogenic species. I. Purification and identification of copper coproporphyrin III. Only a few species, however, have been identified to produce carotenoid pigments (e.g. No skin biopsy was performed. Valeru SP, Rompikuntal PK, Ishikawa T, Vaitkevicius K, Sjling A, Dolganoy N, et al. Indian J Dermatol 2017; 62: 675. Two glands produce sweat: eccrine and apocrine glands. It often begins with antiperspirants. From a medical perspective, the pathogenic species C. diphtheriae (diphtheria), C. ulcerans (diphtheria-like infections), C. tenuis (trichomycosis axillaris), C. minutissimum (erythrasma), and C. striatum (endocarditis) might be of greatest interest. Glasset B, Herbin S, Granier SA, Cavali L, Lafeuille E, Gurin C, et al. Griffith JR. Isolated areolar apocrine chromhidrosis. Here, learn about home care techniques and medical treatments that can reduce or stop the, Sweating in the area around the vagina is normal, but it can sometimes cause discomfort and irritation. Is this an emergency? (As always, talk to your healthcare providerabout your individual situation to receive an accurate diagnosis before beginning any new treatment.). Based on the literature review, there are only 4 bacteria that are confirmed to have resulted in cases of IPCH (Table I): Bacillus species blue IPCH (2, 37, 38): Bacillus is a genus of Gram-positive, sporulating rods that are aerobic or facultatively anaerobic and are widely distributed in the environment (soil, dust, water, food, and plants) (52, 53). The authors have no conflicts of interest to declare. That means the norovirus infection can easily spread to others. This condition can further subdivide into apocrine chromhidrosis and eccrine chromhidrosis, and the treatment depends on type and cause. He or she will likely want to take the necessary steps to rule out potentially more serious medical conditions before making a diagnosis of chromhidrosis. Pseudochromhidrosis results from contact between sweat and dyes, chemicals, or chromogenic bacteria on the skin. Norovirus spreads very easily and quickly in different ways. Weismann K, Poulsen AG, Moller AF, Kobayashi T. A man with a reddish stained wash cloth. Aeruginosa derives from the Latin word for copper rust, referring to the characteristic, pseudomonal discolouration (65). Autofluorescence of clothing as an adjunct in the diagnosis of apocrine chromhidrosis. All swabs and skin scrapings were negative for fungi. Coughing up blood or mucus. Beer K, Oakley H. Axillary chromhidrosis: report of a case, review of the literature and treatment considerations. include protected health information. Chromhidrosis can subdivide into three categories: Apocrine chromhidrosis, eccrine chromhidrosis, and pseudochromhidrosis (pseudo-eccrine chromhidrosis). Two out of 5 swabs from the male patient (pectoral region and foot) yielded the same bacteria. Some people may experience a warm, tingly sensation before the appearance of colored sweat. Kitamura S, Yanagi T, Imafuku K, Hata H, Shimizu H. Lipofuscin deposition causes the pigmentation of apocrine hidrocystoma. overgrowth upon stopping ranitidine. Chromhidrosis is a rare, chronic condition characterized by color in your sweat. LeFeber WP, Golitz LE. Mol Microbiol 2005; 56: 971989. Effect of fetal and adult bovine serum on pyocyanin production in Pseudomonas aeruginosa isolated from clinical and soil samples. 9th ed. Anyone who has chromhidrosis should speak with a healthcare provider if they start to experience symptoms of emotional distress, depression, or anxiety. J Appl Microbiol 2017; 123: 12281236. For evaluation of abnormal colored sweat or any other skin problem, contact our Attleboro, Massachusetts, office at 508-222-1976 or book online to schedule an appointment. Blalock TW, Crowson AN, Danford B. pH measurements of sweat were considered normal (mean/minmax: 5.6/5.16.5). The pH of the skin surface and its impact on the barrier function. (c) Diffuse blue discolouration on the neck. face, axillae, anogenital area, and breast areolae) that excrete small amounts of oily sweat (1, 3). All rights reserved. Skin scrapings for dermatophyte PCR identification were taken from the female and male patient. Accessed June 16, 2022. In other words, it's not your sweat that's colored the color comes from the way your sweat interacts with other things outside your body. Am J Dermatopathol 2014; 36: 853855. Such pigments have, in some cases, been the suggested or documented reason for coloured sweat. Corynebacterium species brown/black IPCH (44, 49, 50): Corynebacterium is a genus of Gram-positive and (mostly) aerobic rods that is widely distributed in nature. It is more common than chromhidrosis. The color may only affect sweat in certain areas or sweat all over the body. B. cereus is an occasional pathogen that can cause various infections mostly associated with its secreted toxins (5255). The scope of this article was, therefore, to report another case of IPCH and to review the literature. Bromhidrosis, also known as osmidrosis or ozochrotia, is an unpleasant or offensive body odour due to any cause including poor hygiene, infections, diet or medications, or inherited metabolic disorders. Regulation of the biosynthesis of coproporphyrin III and its copper complex by oxygen and heavy metal ions. Interestingly, our patients unspecified hypohidrotic condition could, in fact, have been intensified by the use of promethazine: Zahejsky & Rovensky reported a significant reduction in palmar sweating after administration of promethazine in their clinical study (101). Pistone G, Bellomo L, Alaimo R, Bongiorno MR. Pseudochromhidrosis: the role of dermoscopy in diagnosis. Green staining of clothing: a signal for pseudomonal infection. IHS: One of the things weve learned over the years is that no two people sweat exactly the same., Mayo Clinic: Sweating and body odor, StatPearls Publishing: Anatomy, Skin Sweat Glands, StatPearls Publishing: Chromhidrosis, IHS: OnabotulinumtoxinA Injections (Botox). Anyone who has chromhidrosis and experiences any emotional distress should let a healthcare provider know. Those substances might include water-soluble dyes, heavy metals (like copper), excess food coloring or flavoring, as well as certain medications (rifampin, an antibiotic; quinines, an antimalarial; and levodopa, a dopamine precursor used to manage Parkinson's).